Micro Nutrient Kick

MNK isn’t just your general multivitamin. It’s a little MORE.

Yes, most “multivitamins” are practically the same depending on the ingredients. so why MNK?

So the world of “multivitamins” is quite tricky but simple, are they all the same? yes & no, depending on the ingredients and where they came from, how they were processed, etc.

MNK supports the health of your body, basically supporting your immune system and all the wonders around it. certain foods have different impacts on the body, So we put together some of the best fruits, vegetables & herbs for the human body that is 100% backed by scientific studies and more or less, fruit and herbs that the general person does not intake high amounts off.

With high concentrated amounts of these ingredients, formulated correctly is like a natural steroid to the body. It’s like putting jet fuel in your motorbike instead of regular fuel. you get our point? Regular multivitamins or even individual vitamins are normally synthetic or the companies that produce them, don’t focus on the ingredients, where they get them from or they’re produced.

What Is It?

MNK helps the body by supporting every single system in your body, which is incredibly important for a healthy body. It promotes or restores your physiological functioning, which is how your body and organs function. while supporting your immune system and helping it become more “resilient” by providing an adaptogenic formula that allows for balance by lifting up the immune system or bringing it back down to balance whichever direction may be required and building our defence for whatever comes next! It also helps your body balance out the effects of stress and deal with it as quick as possible so your body can move on and focus whats important, SURVIVING.

It’s still a MULTIVITAMIN

Micronutrients help provide nutritional stability in the body and are essential to every diet.  When the body lacks sufficient nutrients, it can’t perform optimally.  Micronutrient deficiency can affect virtually every aspect of the human body including sleep, stress, mood, energy and focus.  Unlike proteins synthesized from amino acids, micronutrients aren’t made in the body, so they must be provided in some other way.

Micronutrients, also known as bioavailable vitamins and minerals, help to regulate mood, mental health, physical health, aging, and physical fitness.  Micronutrients help the body by providing the nutritional building blocks necessary for optimal health.  While essential micronutrients can be found in foods such as raw fruits and vegetables, higher levels may be necessary for those with above average nutritional needs.  

Clinical micronutrient supplementation has become a popular and important way to provide higher levels of bioavailable nutrition than even the healthiest of diets can offer.

Think of the human body as a vehicle with thousands of moving parts.  If a vehicle runs low on gas and oil, it won’t function properly, and over time some serious damage could occur to the engine, transmission and other essential systems.   Micronutrients are like premium fuel for the human body.  The body cannot make all of these micronutrients, so they must be provided in the diet or through proper supplementation.  Research shows that a lack of micronutrients can create serious health problems, and that providing a balance of highly absorbable micronutrients to the body can positively affect overall health in a major way.[1]

In a perfect world, humans would get all the micronutrients they need from the foods they eat.  However, due to a combination of soil depletion, chemical intervention and other factors, there are simply less micronutrients in food today than there were 40+ years ago. [2]  Even the most carefully selected diets no longer provide us with essential levels of vitamins and minerals.  This creates a need for micronutrient supplementation, especially for those with higher than average nutrient needs due to illness, disease or other environmental and genetic factors.

When a person is deficient in micronutrients, they often feel drained and tired.  This is the body’s way of telling us that it needs a nutritional refuel.  The higher quality diet a person has, the more micronutrients they absorb.  Have you ever noticed that eating fast food or processed foods make you feel tired?  This is because while providing a form of sustenance, unhealthy foods do not contain the levels of essential nutrients the body needs to maintain a healthy balance.  Even a diet high in fruits and vegetables often lacks the levels of micronutrients scientists have identified as essential in mitigating or preventing diseases and disorders in many cases.

Physiological Function…what?

Body Functions & Life’s process

Body functions are the physiological functions of body systems. The body's functions are ultimately its cells' functions. Survival is the body's most important business. Survival depends on the body's maintaining or restoring homeostasis, a state of relative constancy, of its internal environment. Homeostasis depends on the body's ceaselessly carrying on many activities. Its major activities or functions are responding to changes in the body's environment, exchanging materials between the environment and cells, metabolizing foods, and integrating all of the body's diverse activities.

The body's ability to perform many of its functions changes gradually over the years. In general, the body performs its functions least well at both ends of life - in infancy and in old age. During childhood, body functions gradually become more and more efficient and effective. During late maturity and old age the opposite is true. They gradually become less and less efficient and effective. During young adulthood, they normally operate with maximum efficiency and effectiveness.

Life Process

All living organisms have certain characteristics that distinguish them from non-living forms. The basic processes of life include organization, metabolism, responsiveness, movements, and reproduction. In humans, who represent the most complex form of life, there are additional requirements such as growth, differentiation, respiration, digestion, and excretion. All of these processes are interrelated. No part of the body, from the smallest cell to a complete body system, works in isolation. All function together, in fine-tuned balance, for the well being of the individual and to maintain life. Disease such as cancer and death represent a disruption of the balance in these processes.

The following are a brief description of the life process:

Organization

At all levels of the organizational scheme, there is a division of labor. Each component has its own job to perform in cooperation with others. Even a single cell, if it loses its integrity or organization, will die.

Metabolism

Metabolism is a broad term that includes all the chemical reactions that occur in the body. One phase of metabolism is catabolism in which complex substances are broken down into simpler building blocks and energy is released.

Responsiveness

Responsiveness or irritability is concerned with detecting changes in the internal or external environments and reacting to that change. It is the act of sensing a stimulus and responding to it.

Movement

There are many types of movement within the body. On the cellular level, molecules move from one place to another. Blood moves from one part of the body to another. The diaphragm moves with every breath. The ability of muscle fibers to shorten and thus to produce movement is called contractility.

Reproduction

For most people, reproduction refers to the formation of a new person, the birth of a baby. In this way, life is transmitted from one generation to the next through reproduction of the organism. In a broader sense, reproduction also refers to the formation of new cells for the replacement and repair of old cells as well as for growth. This is cellular reproduction. Both are essential to the survival of the human race.

Growth

Growth refers to an increase in size either through an increase in the number of cells or through an increase in the size of each individual cell. In order for growth to occur, anabolic processes must occur at a faster rate than catabolic processes.

Differentiation

Differentiation is a developmental process by which unspecialized cells change into specialized cells with distinctive structural and functional characteristics. Through differentiation, cells develop into tissues and organs.

Respiration

Respiration refers to all the processes involved in the exchange of oxygen and carbon dioxide between the cells and the external environment. It includes ventilation, the diffusion of oxygen and carbon dioxide, and the transport of the gases in the blood. Cellular respiration deals with the cell's utilization of oxygen and release of carbon dioxide in its metabolism.

Digestion

Digestion is the process of breaking down complex ingested foods into simple molecules that can be absorbed into the blood and utilized by the body.

Excretion

Excretion is the process that removes the waste products of digestion and metabolism from the body. It gets rid of by-products that the body is unable to use, many of which are toxic and incompatible with life.

The ten life processes described above are not enough to ensure the survival of the individual. In addition to these processes, life depends on certain physical factors from the environment. These include water, oxygen, nutrients, heat, and pressure.

Immune System

The immune system distinguishes self from non-self and eliminates potentially harmful non-self molecules and cells from the body. The immune system also has the capacity to recognize and destroy abnormal cells that derive from host tissues. Any molecule capable of being recognized by the immune system is considered an antigen (Ag).

The skin, cornea, and mucosa of the respiratory, GI, and GU tracts form a physical barrier that is the body's first line of defense. Some of these barriers also have active immune functions:

  • Outer, keratinized epidermis: Keratinocytes in the skin secrete antimicrobial peptides (defensins), and sebaceous and sweat glands secrete microbe-inhibiting substances (eg, lactic acid, fatty acids). Also, many immune cells (eg, mast cells, intraepithelial lymphocytes, antigen-sampling Langerhans cells) reside in the skin.

  • Mucosa of the respiratory, GI, and GU tracts: The mucus contains antimicrobial substances, such as lysozyme, lactoferrin, and secretory IgA antibody (SIgA).

Breaching of anatomic barriers can trigger 2 types of immune response:

  • Innate

  • Acquired

Many molecular components (eg, complement, cytokines, acute phase proteins) participate in both innate and acquired immunity.

Innate immunity

Innate (natural) immunity does not require prior exposure to an antigen (ie, immunologic memory) to be effective. Thus, it can respond immediately to an invader. Innate immunity recognizes mainly antigen molecules that are broadly distributed rather than specific to one organism or cell.

Components include

  • Phagocytic cells

  • Innate lymphoid cells (eg, natural killer [NK] cells)

  • Polymorphonuclear leukocytes

Phagocytic cells (neutrophils in blood and tissues, monocytes in blood, macrophages in tissues) ingest and destroy invading antigens. Attack by phagocytic cells can be facilitated when antigens are coated with antibody (Ab), which is produced as part of acquired immunity, or when complement proteins opsonize antigens.

Natural killer cells kill virus-infected cells and some tumor cells.

Polymorphonuclear leukocytes (neutrophils, eosinophils, basophils) and mononuclear cells (monocytes, macrophages, mast cells) release inflammatory mediators.

Acquired immunity

Acquired (adaptive) immunity requires prior exposure to an antigen and thus takes time to develop after the initial encounter with a new invader. Thereafter, response is quick. The system remembers past exposures and is antigen-specific.

Components include

  • T cells

  • B cells

Acquired immunity includes

  • Cell-mediated immunity: Derived from certain T-cell responses

  • Humoral immunity: Derived from B-cell responses (B cells secrete soluble antigen-specific antibody)

B cells and T cells work together to destroy invaders. Antigen-presenting cells are needed to present antigens to T cells.

Immune Response

Successful immune defense requires activation, regulation, and resolution of the immune response.

Activation

The immune system is activated when a foreign antigen (Ag) is recognized by circulating antibodies (Abs) or cell surface receptors. These cell surface receptors may be

  • Highly specific (antibodies expressed on B cells or T-cell receptors expressed on T cells)

  • Broadly specific (eg, pattern-recognition receptors such as Toll-like, mannose, and scavenger receptors on dendritic and other cells)

Broadly specific receptors recognize common microbial pathogen-associated molecular patterns in ligands, such as gram-negative lipopolysaccharide, gram-positive peptidoglycans, bacterial flagellin, unmethylated cytosine-guanosine dinucleotides (CpG motifs), and viral double-stranded RNA. These receptors can also recognize molecules that are produced by stressed or infected human cells (called damage-associated molecular patterns).

Activation may also occur when antibody-antigen and complement-microorganism complexes bind to surface receptors for the crystallizable fragment (Fc) region of IgG (Fc-gamma R) and for C3b and iC3b.

Once recognized, an antigen, antigen-antibody complex, or complement-microorganism complex is phagocytosed. Most microorganisms are killed after they are phagocytosed, but others inhibit the phagocyte’s intracellular killing ability (eg, mycobacteria that have been engulfed by a macrophage inhibit that cell's killing ability). In such cases, T cell–derived cytokines, particularly interferon-gamma (IFN-gamma), stimulate the phagocyte to produce more lytic enzymes and other microbicidal products and thus enhance its ability to kill or sequester the microorganism.

Unless antigen is rapidly phagocytosed and entirely degraded (an uncommon event), the acquired immune response is recruited. This response begins in

  • The spleen for circulating antigen

  • Regional lymph nodes for tissue antigen

  • Mucosa-associated lymphoid tissues (eg, tonsils, adenoids, Peyer patches) for mucosal antigen

For example, Langerhans dendritic cells in the skin phagocytose antigen and migrate to local lymph nodes; there, peptides derived from the antigen are expressed on the cell surface within class II major histocompatibility complex (MHC) molecules, which present the peptide to CD4 helper T (Th) cells. When the Th cell engages the MHC-peptide complex and receives various costimulatory signals, it is activated to express receptors for the cytokine IL-2 and secretes several cytokines. Each subset of Th cells secretes different combinations of substances and thus effect different immune responses.

Class II MHC molecules typically present peptides derived from extracellular (exogenous) antigen (eg, from many bacteria) to CD4 Th cells; in contrast, class I MHC molecules typically present peptides derived from intracellular (endogenous) antigens (eg, from viruses) to CD8 cytotoxic T cells. The activated cytotoxic T cell then kills the infected cell.

Regulation

The immune response must be regulated to prevent overwhelming damage to the host (eg, anaphylaxis, widespread tissue destruction). Regulatory T cells (most of which express Foxp3 transcription factor) help control the immune response via secretion of immunosuppressive cytokines, such as IL-10 and transforming growth factor-beta (TGF-beta), or via cell contact dependent mechanisms.

These regulatory cells help prevent autoimmune responses and probably help resolve ongoing responses to nonself antigen.

Resolution

The immune response resolves when antigen is sequestered or eliminated from the body. Without stimulation by antigen, cytokine secretion ceases, and activated cytotoxic T cells undergo apoptosis. Apoptosis tags a cell for immediate phagocytosis, which prevents spillage of the cellular contents and development of subsequent inflammation. T and B cells that have differentiated into memory cells are spared this fate.

Geriatrics Essentials

With aging, the immune system becomes less effective in the following ways:

  • The immune system becomes less able to distinguish self from nonself, making autoimmune disorders more common.

  • Macrophages destroy bacteria, cancer cells, and other antigens more slowly, possibly contributing to the increased incidence of cancer among the elderly.

  • T cells respond less quickly to antigens.

  • There are fewer lymphocytes that can respond to new antigens.

  • The aging body produces less complement in response to bacterial infections.

  • Although overall antibody (Ab) concentration does not decline significantly, the binding affinity of antibody to antigen is decreased, possibly contributing to the increased incidence of pneumonia, influenza, infectious endocarditis, and tetanus and the increased risk of death due to these disorders among the elderly. These changes may also partly explain why vaccines are less effective in the elderly.

Having A Resilient Immune System

Have you ever put your hand on something hot and move your hand before you actually touch it? Have you ever got a tickle in your nose and start sneezing?

Your body “overreacts”. It treats everything as life threatening because what if that tickle on your leg was a venomous spider!!

When you get a cold, it’s your immune system that makes you feel tired & energy-less, not the infecting bug. Your immune response determines how sick you feel and how long. The pain you feel with an injury is your response to the trauma, not the injury. so we want to become “tougher”.

over stimulating survival mechanisms will create dramatic responses, excessive mucous, fever, pain, oxidative stress and reactions. we want our immune system to be resilient, to be tougher, be able to respond and recover quickly while being effective & efficient then turn off as quick as possible to protect you from your own defence mechanisms. When our Immune system is balanced & we have no stress from our first line of defence. Our body is ready to launch but capable of being in healing and recovery mode.

when our immune system is balanced and not stimulated, no stress coming from our first line of defense. We are ready to launch our defense efficiently but we are capable of staying in healing and recovery mode as a default when not actively fighting something or over stimulated and hyper-reactive

Overactive Responses

Some people may have overactive survival responses, which can lead to;

  • anxiety/ panic disorders & depression

  • insomnia & poor sleep patterns

  • auto-immunity

  • allergies

  • pain & fatigue syndromes

Innate & Acquired Defence

our “innate defense” mechanism. What we have inherited from our parents via genetics and perinatal events. Once you launch a survival stress response and you survive; your body remembers it for next time, to help keep you alive. The next time you get that stress trigger your body will bring out that new defence system it has added to your innate defense mechanisms, to fight it once again. These are our “acquired defense” mechanisms.

SHORT TERM (ACUTE) SURVIVAL

Our defense mechanisms are designed for survival. Our Acute response to a challenge recruits all systems of the body to either get ready for action or shut down to send all resources to our survival plan.

 Muscles burn what they have and don’t take any extra fuel from the bloodstream. They become insulin resistant to keep the sugar in the blood high to fuel the nerves, brain and immune system.

 Oxidative blasts of free radicals, inflammation and chemical messengers called cytokines flood into bloodstream, liver and all mucosal and skin surfaces to flush, kill and purge any potential microbial threat or poison.

 The liver speeds up its ability to convert toxins, poisons, and venom’s into a water-soluble form to purge out through sweating, vomiting, and diarrhea and forgets about its other maintenance jobs. It also releases more sugar into the bloodstream and just in case of injury it makes your blood gluggy and sticky to be easier to clot in case of a bleeding injury.

 The nervous system changes priorities away from resting, digesting, repairing and reproducing and focuses on gut instincts, intuition, far vision, anxiety, and panic.

 Sexual desire is shut down for long enough to survive at least and reproduction is not an option while needing to fight or run.

  When you are exposed to potential infections; you launch an immediate innate defense at the site of invasion at the mucosa, which is our first line of defense and the most likely place for infection. Simultaneously you initiate a systemic survival response that changes your priorities to survive today and forget the rest.

When exposed to big things like allergens or parasites your body’s innate defense mechanisms are the same; they attack the mucosa and launch a systemic defense strategy. Your body does not wait to see if it is an infection or an allergy, dead or alive.

After a period of time, seconds to minutes your body recognizes that you have launched an acute stress response and it will attempt to shut it down to protect you from your own defense mechanisms.

 If you get another stress trigger while you are still coming down from your previous problem then your body must go again. You will ignore your negative feedback and go again. If this keeps happening due to your stress response going so high in the first place and still trying to come down as in post-traumatic stress disorder (PTSD) or if you experience constant ongoing repetitive daily or hourly stress long-term then you can move into a phase of chronic stress.

 

LONG-TERM (CHRONIC) SURVIVAL

If the stress response is extreme and/or persistent you can get stuck in a survival mode and your body struggles to control your defense mechanisms. Your own innate and acquired survival skills start to damage your body.

 Chronic long-term immune activation, inflammation, and oxidative stress start to attack and destroy your body. Disease occurs through over-reactive immune responses (autoimmunity) where your own immune system gets confused and starts attacking your own body as if it was an invading organism or allergic disorders that leave you in a constant flushing reaction with swelling, itching, mucous and sneezing.

How To Become More “RESILIENT”?

The key is to not allow things to effect you as much. Become tougher, stronger. reduce the burden.

Our food has changed for various reasons, including farming practices, storage techniques, genetic engineering and uses of pesticides. which has resulted in more sugar, less fibre, thinner skins & peels, less seeds and all the other parts that contain the beneficial compounds. Which are natural poisons that control microbial balance in our external and internal environments. Our food is also deficient, lacking micro nutrients. Even organic food, you don’t know if the micro nutrient level is adequate.

nature has provided synergistic co-factors to work with the essential nutrients. If we look at the way your body can utilize essential fatty acids, if you have all the co-factors. Fish oil contains a special oil (EPA), which is great for our brain. if you supply the plant-based precursor from nuts and seeds, along with B vitamins, vitamin C and magnesium, our body can convert into EPA. This is one way co-factors work.

Herbs and Spices help protect us from unnecessary burden from pathogenic microbes, toxic exposure. They dampen down the severity of the damage from the initial exposure and protect our body from our own defence mechanisms that have been released excessively in response to an acute challenge or are stuck in chronic stages of long term dysregulation.

How Does MNK Make Us More RESILIENT?

The Key ingredient to MNK that helps your Immune System become “resilient” is Alma.

Physical barrier

Alma and other factors work together to protect our physical barriers from being stripped by our own defense mechanisms. Frankincense, myrrh, and turmeric are extremely valuable and powerful tools for maintaining our first line of defense. They are very powerful natural anti-inflammatories but unlike most pharmaceutical drugs or a lot of other natural aspirin-like anti-inflammatory compounds they are also anti-inflammatory and soothing to the mucous membranes and prevent permeability and leaky gut wall. Maintaining a tough and resilient mucous membrane.

Other than inflammation, our membranes are also damaged by the infiltration of hyper-reactive immune cells. Cytokines are chemical messengers released immediately with stress and they attract immune cells to the area to instigate the inflammatory attack and launch indiscriminate chemical attacks with oxidative bursts of free radicals and other damaging compounds like histamine.

 

Bio-Barrier

Our ratios between good and bad microbes living in our mucous on our mucosal membranes have many contributing factors; genetics, environmental exposure, hygiene, dietary macronutrient ratios and fiber (prebiotics), dietary polyphenols and poisons (modbiotics), pesticides on our foods and antimicrobial drugs in our foods (antibiotics).

 Using specific tools in our diet to;

Reduce the dose of exposure to pathogenic microbes through antimicrobial actions; basically, killing off the bad or blocking their entry through or adhesion to our membranes before our immune system has to deal with them. Reishi, amla, frankincense, myrrh, turmeric, and artemisia have potent antimicrobial actions active against multiple pathogenic virus, bacteria, fungi and parasites summarized below.

ANTIBACTERIAL

Amla may help reduce bacterial infections; Staphylococcus aureus, Staphylococcus saprophyticus, Escherichia coli, Enterococcus faecalis, Enterococcus cloacae, Proteus vulgaris and Klebsiella pneumoniae[xxii] and Strep infections, reducing throat infections, firmicute dominance and prevent dental caries. [xxiii]

ANTIVIRAL

Amla may help to stop HSV herpes and HPV warts virus flare-ups and infection by inhibiting attachment, penetration, infection, and replication. [xxx][xxxi] Amla may also be effective against Coxsackie B virus and protects against the damage from viral infection. [xxxii][xxxiii]

 Amla inhibits candida adhesion to the mucosa. [xlvii][xlviii]

NRF2 activators

Our NRF2 gene is our resilient gene. When activated, NRF2 genes initiate a cascade of events to activate our protectant anti-inflammatory, anti-oxidant, detoxifying and anti-stress pathways to protect us from invading infections, abnormal cells, toxic exposure, poison, venom, pollution, radiation or protect our own tissues from our own defense mechanisms. Once things get past our barriers it is the NRF2 gene that we need to activate to survive.

 NRF2 gene activation is being researched heavily as a doomsday prepping strategy for the unknown future. Our world is changing so fast we need to work with what we have as we can’t rely on evolution changing us fast enough.

Amla herb directly is a powerful NRF2 activator [xcvii] that also yields a strong dose of vitamin C [xcviii][xcix] and bioflavonoids including rutin and quercetin[c] as essential nutritional cofactors in the NRF2 antioxidant[ci] and anti-inflammatory mechanisms protection pathways

Inflammation and Pain relief

Inflammation and pain can form a vicious cycle that is damaging, stressful and exhausting. Other than NRF2 activation, these compounds also help reduce pain and inflammation through other mechanisms to remove the burden.

Myrrh has been shown to help with arthritis, headaches, ear and oral mucosal inflammation and reduce pain sensitivity.  Reishi is anti-inflammatory and pain reliever and as is Amla. 

 Liver protectants and detoxification support

Amla  has been shown to be superior to arguably the most famous “liver herb” silymarin and shown to be superior due to the inclusion of the nutritional co-factors of vitamin c and flavonoids as well as the hepatoprotective polyphenols. This may help to protect you from the toxicity of such things as cadmium exposure

 Anti-Stress & Resilience

Another key ingredient of MNK which also has a massive role with helping the resilience of the immune system and also plays another role with balancing out the effects of stress, is holy basil (tulsi). Holy basil is Considered as a potent adaptogen, tulsi has a unique combination of pharmacological actions that promote wellbeing and resilience. While the concept of an “adaptogen,” or herb that helps with the adaptation to stress and the promotion of homeostasis, is not widely used in Western medicine, Western science has revealed that tulsi does indeed possess many pharmacological actions that fulfill this purpose.

There is mounting evidence that tulsi can address physical, chemical, metabolic and psychological stress through a unique combination of pharmacological actions. Tulsi has been found to protect organs and tissues against chemical stress from industrial pollutants and heavy metals, and physical stress from prolonged physical exertion, ischemia, physical restraint and exposure to cold and excessive noise. Tulsi has also been shown to counter metabolic stress through normalization of blood glucose, blood pressure and lipid levels, and psychological stress through positive effects on memory and cognitive function and through its anxiolytic and anti-depressant properties. Tulsi's broad-spectrum antimicrobial activity, which includes activity against a range of pathogens.

Tulsi is also credited with giving luster to the complexion, sweetness to the voice and fostering beauty, intelligence, stamina and a calm emotional disposition.[3,4,5,6] In addition to these health-promoting properties, tulsi is recommended as a treatment for a range of conditions including anxiety, cough, asthma, diarrhea, fever, dysentery, arthritis, eye diseases, otalgia, indigestion, hiccups, vomiting, gastric, cardiac and genitourinary disorders, back pain, skin diseases, ringworm, insect, snake and scorpion bites and malaria.[3,5,6,7]

The medicinal properties of tulsi have been studied in hundreds of scientific studies including in vitro, animal and human experiments. These studies reveal that tulsi has a unique combination of actions that include: Antimicrobial (including antibacterial, antiviral, antifungal, antiprotozoal, antimalarial, anthelmintic), mosquito repellent, anti-diarrheal, anti-oxidant, anti-cataract, anti-inflammatory, chemopreventive, radioprotective, hepato-protective, neuro-protective, cardio-protective, anti-diabetic, anti-hypercholesterolemia, anti-hypertensive, anti-carcinogenic, analgesic, anti-pyretic, anti-allergic, immunomodulatory, central nervous system depressant, memory enhancement, anti-asthmatic, anti-tussive, diaphoretic, anti-thyroid, anti-fertility, anti-ulcer, anti-emetic, anti-spasmodic, anti-arthritic, adaptogenic, anti-stress, anti-cataract, anti-leukodermal and anti-coagulant activities.[4,5,6,7] These pharmacological actions help the body and mind cope with a wide range of chemical, physical, infectious and emotional stresses and restore physiological and psychological function.

Physical stress

The actions that protect against the toxic effects of chemicals and radiation also help to address the toxic effects of many physical stressors. Prolonged physical exertion, physical restraint, exposure to cold and excessive noise disturb homeostasis by inducing physiological and metabolic stress. When the capacity to adapt to these stressors is exceeded, maladaptation occurs resulting in damage to biochemical pathways, organ function and health. Through enhancing various cellular and physiological adaptive functions, adaptogenic herbs such as tulsi are able to protect against this damage.

Studies using forced-swimming, restraint and cold-exposure stress in laboratory animals have shown that tulsi enhances aerobic metabolism, improves swimming time, reduces oxidative tissue damage and normalizes many physiological and biochemical parameters caused by physical stressors. Similarly, experimental studies have shown that tulsi helps reduce the effects of acute and chronic noise-induced stress in experimental animals, with enhancement of neurotransmitter and oxidative stress levels in discrete brain regions along with improved immune, ECG and corticosteroid responses.[42,43,44,45]

Infection protection

Modern research has revealed that tulsi has anti-bacterial, anti-viral and anti-fungal activity[71] that includes activity against many pathogens responsible for human infections. Tulsi has also been shown to boost defenses against infective threats by enhancing immune responses in nonstressed and stressed animals[72,73,74,75,76,77] and healthy humans.[78] While no human trials have been published, there is experimental evidence that tulsi may help in the treatment of various human bacterial infections including urinary tract infections,[79] skin and wound infections,[80] typhoid fever,[81] cholera,[82] tuberculosis,[83] gonorrhea,[84] acne,[85] herpes simplex,[86] leishmaniasis,[87] various pneumonias[88] and fungal infections,[89,90,91,92] as well as mosquito-borne diseases such as dengue, malaria and filariasis.[93,94,95]

Mental stress

In addition to physical, toxic and infective stress, modern living is associated with heightened levels of psychological stress caused by the many demands and fast pace of modern life. This stress compounds the toxic effects of chemical pollutants and the constant fear of pervasive toxic chemicals can itself lead to even further stress and anxiety that may be just as toxic as the chemicals causing it. While the reality of daily chemical exposure cannot be denied, regular consumption of tulsi not only helps protect and detoxify the body's cells and organs, it can also help reduce toxic stress by relaxing and calming the mind and offering many psychological benefits including anti-depressant activity and positive effects on memory and cognitive function.

Want More Info

we hope that this is enough info for you to understand what MNK does. If you’d like to know the other ingredients, you can find them in our blog or with the MNK product